Models of Intrauterine growth restriction and fetal programming in rabbits
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چکیده
منابع مشابه
Evaluation of Abdominal Fetal Electrocardiography in Early Intrauterine Growth Restriction
Objectives: This descriptive study was performed to evaluate the capability of a non-invasive transabdominal electrocardiographic system to extract clear fetal electrocardiographic (FECG) measurements from intrauterine growth restricted (IUGR) fetuses and to assess whether abdominal FECG parameters can be developed as markers for evaluating the fetal cardiac status in IUGR. Methods: Transabdomi...
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UNLABELLED One of the most important causes of perinatal mortality and morbidity complicating significant percentage pregnancies is intrauterine growth restriction (IUGR). Fetal growth restriction is the main cause of intrauterine fetal death and the second leading cause of death in the neonatal period. Numerous studies in different populations reveal an association between intrauterine growth ...
متن کاملExtrinsic Factors Influencing Fetal Deformations and Intrauterine Growth Restriction
The causes of intrauterine growth restriction (IUGR) are multifactorial with both intrinsic and extrinsic influences. While many studies focus on the intrinsic pathological causes, the possible long-term consequences resulting from extrinsic intrauterine physiological constraints merit additional consideration and further investigation. Infants with IUGR can exhibit early symmetric or late asym...
متن کاملPrenatal programming of insulin secretion in intrauterine growth restriction.
Intrauterine growth restriction (IUGR) impairs insulin secretion in humans and in animal models of IUGR. Several underlying mechanisms have been implicated, including decreased expression of molecular regulators of β-cell mass and function, in some cases shown to be due to epigenetic changes initiated by an adverse fetal environment. Alterations in cell cycle progression contribute to loss of β...
متن کاملIntrauterine repair of gastroschisis in fetal rabbits.
OBJECTIVE Infants with gastroschisis (GS) still face severe morbidity. Prenatal closure may prevent gastrointestinal organ damage, but intrauterine GS repair (GSR) has not been established yet. METHODS In New Zealand White rabbits we developed and compared GS versus GSR: creation of GS was achieved by hysterotomy, right-sided laparotomy of the fetus and pressure on the abdominal wall to provo...
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ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2019
ISSN: 1040-452X,1098-2795
DOI: 10.1002/mrd.23271